Dror Emmanuel WARSCHAWSKI

Born May 25th, 1969

RESEARCH EXPERIENCE

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Institut de Biologie Physico-Chimique, Paris (France)

Since 1998 Research associate at the Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, CNRS - UMR 7099. Advisor: Bruno Miroux.

Université du Québec à Montréal, Québec (Canada)

2007 "Biophysical study of bicelles: NMR, atomic force microscopy, mass spectrometry, infra-red spectroscopy", Sabbatical, 1 year. Advisor: Isabelle Marcotte

Guelph University, Ontario (Canada)

1997 "Structural study of membrane peptides by solid-state NMR", Post-Doctorate, 3 months. Advisor: James H. Davis

Massachusetts Institute of Technology, Cambridge (USA)

95-97 "Lipids and membrane peptides under physiological conditions: structural and dynamical studies using solid-state NMR", Post-doctorate: 2 years. Advisor: Professor Robert G. Griffin

Université Paris Diderot, Paris (France)

92-95 "Biomembranes, model membranes: new approaches using magic-angle spinning solid-state NMR", Ph. D. in Molecular Biophysics , 3 years. Advisor: Professor Philippe F. Devaux

Guelph University, Ontario (Canada)

1992 "Lipid studies by solid-state NMR", 3 months. Advisor: Professor James H. Davis

Institut de Biologie Physico-Chimique, Paris (France)

1991 "Red blood cell study by EPR", 3 months. Advisor: Doctor Alain Zachowski

Institut Curie, Paris (France)

1990 "Study of an ion-plasma collision", 2 months

TEACHING EXPERIENCE

On the internet

I manage the mailing list of NMR laboratories around the world, as well as the two databases for protein structures determined by NMR:

since 2009 Teaching biological NMR for the MSc "Protein engineering and industrial applications"

since 2006 Teaching solid-state NMR for the MSc "Molecular and Cellular Biophysics"

since 2005 Teaching biological NMR for the MSc "Structure, Proteomics and Functional Genetics"

since 2001 Teaching practical NMR for the MSc in Biology

Université Paris-Sud 11

2006 Teaching biological solid-state NMR for the MSc "Structural and Functional Engineering of Biomolecules"

Université Paris Descartes

2004-2006 Member of the commission de spécialistes 31-32ème section

since 2001 Teaching solid-state NMR for the MSc "Chemical and Biological Analyses"

Université Paris XIII Nord

2002-2009 Member of the commission de spécialistes 28ème section

Ecole Normale Supérieure, Paris

2006-2009 Teaching biological solid-state NMR for the MSc in Biology

2001 Teaching solid-state NMR for professors of "classes préparatoires aux grandes écoles"

Institut de Biologie Physico-Chimique, Paris

since 1998 Tutoring post-docs, PhD, MSc and BSc students

EDUCATION AND HONORS

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Université Paris Diderot

2006 Habilitation to Direct Researches, Physics

92-95 Recipient of a fellowship from the Ministère de l'Enseignement Supérieur et de la Recherche for a Ph. D. in Molecular Biophysics, Cum Magna Laude. Advisor: Philippe F. Devaux

91-92 DEA de Biophysique Moléculaire and Magistère de Physique, Honors AB

90-91 Maitrise de Physique (Masters in Physics), Honors AB

BIBLIOGRAPHY

A. Abdine, M. A. Verhoeven and D. E. Warschawski "Cell-free expression and labeling strategies for a new decade in solid-state NMR" New Biotechnol. 28:272-276 (2011)

A. Abdine, M. A. Verhoeven, K.-H. Park, A. Ghazi, E. Guittet, C. Berrier, C. Van Heijenoort and D. E. Warschawski "Structural study of the membrane protein MscL using cell-free expression and solid-state NMR" J. Magn. Reson. 204:155-159 (2010)

M. N. Triba, P. F. Devaux and D. E. Warschawski "Effects of lipid chain length and unsaturation on bicelles stability. A phosphorus NMR study" Biophys. J. 91:1357-1367 (2006)

M. N. Triba, M. Zoonens, J.-L. Popot, P. F. Devaux and D. E. Warschawski "Reconstitution and alignment by a magnetic field of a β-barrel membrane protein in bicelles" Eur. Biophys. J. 35:268-275 (2006)

D. E. Warschawski and P. F. Devaux "1H-13C polarization transfer in membranes: A tool for probing lipid dynamics and the effect of cholesterol" J. Magn. Reson. 177:166-171 (2005)

D. E. Warschawski and P. F. Devaux "Order parameters of unsaturated phospholipids in membranes and the effect of cholesterol: a 1H-13C solid-state NMR study at natural abundance" Eur. Biophys. J. 34:987-996 (2005)

M. N. Triba, D. E. Warschawski and P. F. Devaux "Bicelles: disks or perforated lamellae?" Eur. Biophys. J. 34:710 (2005)

O. Wattraint, D. E. Warschawski and C. Sarazin "Tethered or adsorbed supported lipid bilayers in nanotubes characterized by deuterium magic angle spinning NMR spectroscopy" Langmuir 21:3226-3228 (2005)

M.N. Triba, D. E. Warschawski and P. F. Devaux "Reinvestigation by phosphorus NMR of lipid distribution in bicelles" Biophys. J. 88:1887–1901 (2005)

M. N. Triba, M. Traïkia, D. E. Warschawski, L. Nicolas-Morgantini, A. Lety, P. Gilard and P. F. Devaux "Proton Magic Angle Spinning-NMR Investigation of Surfactant Aqueous Suspensions" Journal of Colloid and Interface Science 274:341-345 (2004)

D. E. Warschawski and P. F. Devaux "Using DROSS to study the order of unsaturated lipid, sphingolipids and lipid / cholesterol interactions" Eur. Biophs. J. 32:288 (2003)

F. Ferrage, M. Zoonens, D. E. Warschawski, J.-L. Popot and G. Bodenhausen "Slow Diffusion of Macromolecular Assemblies Measured by a New Pulsed Field Gradient NMR Method" J. Am. Chem. Soc. 125:2541-2545 (2003)

Correction: J. Am. Chem. Soc. 126:5654 (2004)

M. Traïkia, D. E. Warschawski, O. Lambert, J.-L. Rigaud and P. F. Devaux "Asymmetrical Membranes and Surface Tension" Biophys. J. 83:1443-1454 (2002)

N. Tsapis, R. Ober, A. Chaffotte, D. E. Warschawski, J. Everett, J. Kauffman, P. Kahn, M. Waks and W. Urbach "Modification of the elastic constants of a peptide-decorated lamellar phase", Langmuir 18:4384-4392 (2002)

D. E. Warschawski and P.F. Devaux "Polarisation transfer in lipid membranes" J. Magn. Resonance 145:367-372 (2000)

M. Traikia, D. E. Warschawski, M. Recouvreur, J. Cartaud and P. F. Devaux "Formation of unilameller vesicles by repetitive freeze-thaw cycles: characterization by electron microscopy and 31P-NMR" Eur. Biophs. J. 29:184-195 (2000)

D. E. Warschawski, M. Traikia, P. F. Devaux and G. Bodenhausen, "Solid-State NMR for the study of membrane systems: The use of anisotropic interactions" Biochimie 80:437-450 (1998)

D. E. Warschawski, J. D. Gross and R. G. Griffin, "Effects of membrane peptide dynamics on high-resolution magic-angle spinning NMR" Journal de Chimie Physique 95:460-466 (1998)

D. E. Warschawski, J. D. Gross and R. G. Griffin, "Dynamics of gramicidin A deduced from high-resolution magic-angle spinning NMR" Biophys. J. 72:A325 (1997)

J. D. Gross, D. E. Warschawski and R. G. Griffin, "Dipolar recoupling in MAS NMR: A probe for segmental order in lipid bilayers" J. Am. Chem. Soc. 119:796-802 (1997)

D. E. Warschawski, P. Fellmann and P. F. Devaux, "High resolution 31P-1H two-dimensional Nuclear Magnetic Resonance spectra of unsonicated lipid mixtures spinning at the magic-angle" Eur. Biophys. J. 25:131-137 (1996)

J. D. Gross, P. R. Costa, J.-P. Dubacq, D. E. Warschawski, P.-N. Lirsac, P. F. Devaux and R. G. Griffin, "Multidimensional NMR in lipid systems. Coherence transfer through J couplings under MAS" J. Magn. Reson. B106:187-190 (1995)

D. E. Warschawski and P. F. Devaux, "Water suppression in 1H MASS NMR spectra of lipids and biological membranes" J. Magn. Reson. B106:76-79 (1995)

PRESENTATIONS

Organisation of the Workshop on NMR of Biological Solids in Paris (France, 2009)


Oral presentation at the Cell-Free Protein Expression Meeting in Birmingham (UK, 2009)

Oral presentation at the Réunion du Réseau RMN dans le Grand Bassin Parisien in Paris (France, 2009)

Oral presentation at the Workshop on NMR of Biological Solids in Paris (France, 2009)

Oral presentation at the GDR Protéines Membranaires at Les Houches (France, 2009)

Oral presentation at the Montreal Structural Biology Meeting at the Mont-Saint-Hilaire (Canada, 2007)

Oral presentation at the MOOT NMR Symposium in Sainte-Adèle (Canada, 2007)

Oral presentation at the GDR Protéines membranaires et assemblages colloïdaux in Fréjus (France, 2005)

Oral presentation at the GEIMM conference in Dinard (France, 2004)

Oral presentation at the GDR Protéines membranaires et assemblages colloïdaux in Erdeven (France, 2003)

Oral presentation at the Conférence RMN du solide Bruker in Caen (France, 2002)

Oral presentation at the Atelier Peptides Hydrophobes in Garchy (France, 2001)

Oral presentation at the Journée RMN du solide in Orléans (France, 2001)

Oral presentation at the Réunion PCV - Fusion membranaire in Toulouse (France, 2000)

Oral presentation at the Atelier INSERM in Le Vésinet (France, 1999)

Oral presentation at the Alpine Conference on Solid-State NMR in Chamonix (France, 1999)

Oral presentation at the Conférence RMN Bruker in Obernai (France, 1998)

Oral presentation at the Groupe d'Etude de Résonance Magnétique in Oléron (France, 1997)

Oral presentation at the European Experimental NMR Conference in Paris (France, 1996)

Presentation of a poster at the Euromar in Florence (Italy, 2010)

Presentation of a poster at the Alpine Conference on Solid-State NMR in Chamonix (France, 2009)

Presentation of a poster at the Experimental NMR Conference in Asilomar (USA, 2009)

Presentation of a poster at the Alpine Conference on Solid-State NMR in Chamonix (France, 2005)

Presentation of a poster at the International Biophysics Congress in Montpellier (France 2005)

Presentation of a poster at the European Biophysics Congress in Alicante (Spain 2003)

Presentation of a poster at the Experimental NMR Conference in Savannah, Georgia (USA, 2003)

Presentation of a poster at the Société Française de Biophysique in Annecy (France, 2002)

Presentation of a poster at the Groupe d'Etude de Résonance Magnétique in Southampton (UK, 2002)

Presentation of a poster at the Alpine Conference on Solid-State NMR in Chamonix (France, 2001)

Presentation of a poster at the International Conference of Magnetic Resonance on Biological Systems in Firenze (Italy, 2000)

Presentation of a poster at the Alpine Conference on Solid-State NMR in Chamonix (France, 1999)

Presentation of a poster at the Groupe d'Etude de Résonance Magnétique in Oléron (France, 1997)

Presentation of a poster at the Biophysical Society in New-Orleans (USA, 1997)

Presentation of a poster at the International Conference of Magnetic Resonance on Biological Systems in Keystone (USA, 1996)

Presentation of a poster at the European Experimental NMR Conference in Paris (France, 1996)

Presentation of a poster at the Experimental NMR Conference in Asilomar (USA, 1996)

Presentation of a poster at the Experimental NMR Conference in Boston (USA, 1995)

Presentation of a poster at the Biophysical Society in San Francisco (USA, 1995)

Presentation of a poster at the International Conference of Magnetic Resonance on Biological Systems in Veldhoven (The Netherlands, 1994)

Presentation of a poster at the European Experimental NMR Conference in Oulu (Finland, 1994)

Presentation of a poster at the meeting of the Société Française de Biophysique in Orléans (France, 1992)

REVIEWS

For: Biochemistry, Biophysical Journal, Colloid and Surfaces, CRAS Chimie, European Biophysics Journal, FEBS letters, Magnetic Resonance in Chemistry, Magnetic Resonance in Medicine...

SKILLS

Computer languages used: BASIC, PASCAL, UNIX and VMS

Synthesis and purification of membrane peptides

INTERESTS

Traveling all over the world

Webmaster of several websites and mailing lists